What is Rejuran (Salmon DNA) treatment in Korea?

March 25, 2026

What is Rejuran (Salmon DNA) treatment in Korea?

Rejuran is one of the most popular skin regeneration treatments in Korea, especially in clinics across Seoul. Often referred to as a “salmon DNA injection,” it is designed to repair damaged skin, improve elasticity, and restore overall skin health rather than simply adding volume.


What Exactly Is Rejuran?

Rejuran is an injectable treatment made from polynucleotides (PN), which are derived from salmon DNA.

Key characteristics:

  • Biocompatible and highly purified DNA fragments
  • Stimulates natural skin regeneration
  • Improves skin structure at a cellular level

Unlike fillers or Botox, Rejuran does not change facial shape—it focuses on improving skin quality from within.


What Does Rejuran Do?

Rejuran works by activating the skin’s natural healing process.

Main effects:

  • Boosts collagen production
  • Repairs damaged skin tissue
  • Strengthens skin barrier
  • Improves elasticity and fine lines
  • Reduces redness and inflammation

This is why it is often called a “skin healer” in Korean dermatology.


What Is the Treatment Process Like?

Rejuran is administered through multiple micro-injections across the face.

Typical procedure:

  • Numbing cream applied (20–30 minutes)
  • Small injections evenly distributed
  • Treatment time: about 20–30 minutes

After treatment:

  • Small bumps (papules) may appear temporarily
  • Mild redness or swelling can last 1–2 days

There is minimal downtime, but the injection process can feel slightly uncomfortable.


How Many Sessions Are Needed?

Rejuran is not a one-time treatment—it works best as a course.

Typical plan:

  • 3–4 sessions initially (every 3–4 weeks)
  • Maintenance every 6–12 months

Results improve gradually as the skin regenerates over time.


Who Is Rejuran Best For?

Rejuran is suitable for a wide range of skin types.

Ideal for:

  • Damaged or sensitive skin
  • Acne scars or uneven texture
  • Fine lines and early aging
  • Redness and weakened skin barrier

It is especially popular among patients looking for natural, subtle skin improvement.


Cost of Rejuran in Korea

Typical price range in Seoul:

  • ₩250,000 – ₩400,000 per session (2cc standard)
  • Higher volumes or premium clinics: ₩500,000+

Package deals are commonly available and reduce overall cost.


Why Is Rejuran So Popular in Korea?

Rejuran fits perfectly with Korea’s skincare philosophy of long-term skin health over quick fixes.

Reasons for popularity:

  • Natural-looking results
  • Focus on skin quality rather than volume
  • Works well with other treatments (lasers, boosters)
  • Widely available and relatively affordable

It is often used as a foundation treatment in Korean dermatology.


Final Thoughts

Rejuran (salmon DNA treatment) is a unique regenerative procedure that improves skin from the inside out. In Seoul, it is one of the most trusted treatments for patients seeking healthier, stronger, and more youthful skin without altering facial structure.

  • Rejuran = skin repair, regeneration, and barrier strengthening
  • Made from polynucleotides (salmon DNA)
  • Requires multiple sessions for best results
  • Minimal downtime with gradual improvement
  • Ideal for natural, long-term skin enhancement


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